Asia/Pacific Presentations

13 presentations showcasing regional R innovations

Overview

The Asia/Pacific session featured 13 presentations covering a wide range of topics from open-source culture and data strategy to AI implementation and clinical reporting automation. These presentations showcase the growing adoption of R and innovative applications across pharmaceutical companies in the region.

Strategic & Cultural Topics

Open-Source Culture and Data Strategy in SHIONOGI

Yoshitake Kitanishi (SHIONOGI)

Presentation on creating value through open-source adoption and data strategy implementation at SHIONOGI.

Topics likely covered:

Open-source adoption strategy
Data-driven decision making
Creating organizational value
Cultural transformation

Strategically Assisting Statistical Programmers (SAS2R)

KuenHung Lin

Framework for supporting statistical programmers transitioning from SAS to R.

Focus areas:

Migration strategies
Training approaches
Support systems
Success metrics

Technical Implementations

Side-by-Side by Design: Pharma Data Handling

Yutaka Morioka, Yuki Nakagawa

Comprehensive comparison of data handling approaches in pharma using merge, join, match, and hash operations in R.

Key concepts:

Data merging strategies
Join operations optimization
Hash table implementations
Performance comparisons

Risk Assessment Deep Dive

Ryo Nakaya

In-depth exploration of risk assessment methodologies and tools for pharmaceutical R packages.

Topics:

Package risk evaluation
Validation frameworks
Quality metrics
Decision criteria

Automation & Efficiency

Leverage Template-Based Automated Reporting on DMC Materials

Nina Han, Peng Zhang

Automation of Data Monitoring Committee (DMC) materials preparation using template-based approaches.

Benefits:

Reduced preparation time
Consistency across reports
Error reduction
Reproducibility

Dynamic Creation of Kaplan-Meier Plots and Summary Tables

Takumi Imamura, Takahiro Hasegawa

R Shiny application for interactive survival data visualization and table generation.

Features:

Interactive K-M plots
Dynamic summary measures
User-friendly interface
Export capabilities

autoslideR: Streamlining Slide Deck Generation

Yolanda Zhou, Joe Zhu (Roche)

R package for automating clinical reporting slide decks (also presented in EU/US sessions).

Key advantages:

0.5-4 days time savings
Multiple event types supported
Customizable layouts
Placeholder functionality

Resources: pharmaverse.github.io/examples/digit_files/autoslider.html

R Adoption & Strategy

From Harmony to Hybrid: Charting a Course for R Adoption

Joe Zhu

Practical strategies for R adoption in pharmaceutical organizations.

Topics:

Adoption frameworks
Hybrid approaches (SAS + R)
Change management
Success factors

Emerging Trend of LLM Development in R

Mia Chen, Peng Zhang

Overview of Large Language Model implementation trends in R ecosystem.

Coverage:

Current LLM packages in R
Integration patterns
Use cases in pharma
Future directions

Specialized Applications

An R Package for Pretest Probability Models for CAD

Jeremy Selva

Package consolidating pretest probability models and guidelines for Coronary Artery Disease.

Features:

Multiple model implementations
Guideline integration
Clinical utility
Validation support

Enhancing e-CRT Creation for PMDA with Vibe Coding

Naoki Yoshida

R Shiny app development for PMDA (Japan’s regulatory agency) electronic Case Report Tabulation using innovative “Vibe Coding” approach.

Innovation:

Rapid development methodology
Regulatory-ready outputs
User-friendly interface
Efficiency gains

AI & Advanced Methods

{meRlin}: Context-Aware AI Assistant for Clinical Programming

Steven Brooks, Pietro Mascheroni, Xiecheng Gu

AI assistant specifically designed for clinical programming workflows.

Capabilities:

Context-aware code suggestions
Clinical programming patterns
Integration with development environment
Domain-specific knowledge

Improving Precision Healthcare for Under-Represented Populations

Jimmy Breen

Application of R in advancing precision healthcare for genetically diverse and under-represented global populations.

Focus:

Genetic diversity considerations
Population-specific analyses
Healthcare equity
Precision medicine approaches

Exploring AI Tools in Clinical Trial Data Analysis

Terry Zhang

Survey and exploration of AI tools applicable to clinical trial data analysis.

Coverage:

Available AI tools
Use case demonstrations
Integration strategies
Practical applications

cgmguru: Automated Glycemic Event Detection

Sang Ho Park

R package for automated detection of glycemic events from continuous glucose monitoring data.

Features:

Event detection algorithms
Automated analysis
Clinical relevance
Validation metrics

Reporting & Documentation

Interactive and Reproducible Reports with Quarto

Jaspreet Pabla

Creating interactive, reproducible clinical reports using Quarto.

Advantages:

Multi-format output
Interactivity options
Reproducibility
Modern publishing

Using ARD with {cards} for PMDA Oncology Inquiries

Shunsuke Goto

Application of Analysis Results Data using {cards} package for responding to PMDA oncology regulatory inquiries.

Benefits:

Structured data approach
Rapid response capability
Consistency
Traceability

Practical Tips & Tools

Reach for R Low Hanging Fruit for Faster Results

Sunil Gupta

Identifying and implementing quick wins with R for immediate productivity gains.

Topics:

Quick wins identification
Practical implementations
Efficiency improvements
Getting started tips

MedxR Package: Bridging FDA and Health Canada Drug Data

Renzo Cáceres Rossi

R package providing access to regulatory drug data from FDA and Health Canada.

Features:

Unified data access
API integration
Data standardization
Research facilitation

risk.assessr: Extending Package Validation

Hugo Bottois

Extension of risk assessment tools for package validation processes.

Enhancements:

Validation workflow support
Extended metrics
Integration capabilities
Reporting features

Code Review for Compliance: Validated R Workflows

Alexandros Kouretsis

Best practices for code review in validated R workflows for pharmaceutical compliance.

Topics:

Review strategies
Compliance requirements
Quality assurance
Documentation

Web-Based R Application for Patient Enrollment Forecasting

Akifumi Okayama, Motoki Oe, Nobushige Matsuoka

Shiny application for forecasting patient enrollment in clinical trials.

Features:

Forecasting models
Interactive interface
Scenario planning
Decision support

🔑 Regional Themes

1. Regulatory Focus

Strong emphasis on PMDA (Japan) regulatory requirements with specialized tools and approaches.

2. Practical Implementation

Focus on real-world applications and efficiency improvements in daily workflows.

3. AI Adoption

Growing interest in AI/LLM tools tailored for clinical programming and analysis.

4. Open Source Movement

Increasing adoption of open-source culture and collaborative development.

5. Cultural Considerations

Presentations addressing unique challenges and opportunities in Asia/Pacific markets including:

Under-represented populations
Regional regulatory requirements
Local healthcare systems
Genetic diversity

📊 Topic Distribution

Automation & Tools

AI & Advanced Methods

Strategy & Culture

🌏 Geographic Insights

The Asia/Pacific presentations demonstrate:

Strong R adoption across major pharma companies in the region
Innovation in automation for regulatory compliance (especially PMDA)
Focus on practical tools addressing regional-specific needs
Growing AI integration in clinical workflows
Emphasis on efficiency and time-saving solutions

Asia/Pacific Presentations from R/Pharma 2025 Conference | Last updated: November 2025

--- title: "Asia/Pacific Presentations" subtitle: "13 presentations showcasing regional R innovations" toc: true --- ## Overview The Asia/Pacific session featured 13 presentations covering a wide range of topics from open-source culture and data strategy to AI implementation and clinical reporting automation. These presentations showcase the growing adoption of R and innovative applications across pharmaceutical companies in the region. ------------------------------------------------------------------------ ## Strategic & Cultural Topics ### Open-Source Culture and Data Strategy in SHIONOGI **Yoshitake Kitanishi** (SHIONOGI) Presentation on creating value through open-source adoption and data strategy implementation at SHIONOGI. **Topics likely covered:** - Open-source adoption strategy - Data-driven decision making - Creating organizational value - Cultural transformation ------------------------------------------------------------------------ ### Strategically Assisting Statistical Programmers (SAS2R) **KuenHung Lin** Framework for supporting statistical programmers transitioning from SAS to R. **Focus areas:** - Migration strategies - Training approaches - Support systems - Success metrics ------------------------------------------------------------------------ ## Technical Implementations ### Side-by-Side by Design: Pharma Data Handling **Yutaka Morioka, Yuki Nakagawa** Comprehensive comparison of data handling approaches in pharma using merge, join, match, and hash operations in R. **Key concepts:** - Data merging strategies - Join operations optimization - Hash table implementations - Performance comparisons ------------------------------------------------------------------------ ### Risk Assessment Deep Dive **Ryo Nakaya** In-depth exploration of risk assessment methodologies and tools for pharmaceutical R packages. **Topics:** - Package risk evaluation - Validation frameworks - Quality metrics - Decision criteria ------------------------------------------------------------------------ ## Automation & Efficiency ### Leverage Template-Based Automated Reporting on DMC Materials **Nina Han, Peng Zhang** Automation of Data Monitoring Committee (DMC) materials preparation using template-based approaches. **Benefits:** - Reduced preparation time - Consistency across reports - Error reduction - Reproducibility ------------------------------------------------------------------------ ### Dynamic Creation of Kaplan-Meier Plots and Summary Tables **Takumi Imamura, Takahiro Hasegawa** R Shiny application for interactive survival data visualization and table generation. **Features:** - Interactive K-M plots - Dynamic summary measures - User-friendly interface - Export capabilities ------------------------------------------------------------------------ ### autoslideR: Streamlining Slide Deck Generation **Yolanda Zhou, Joe Zhu** (Roche) R package for automating clinical reporting slide decks (also presented in EU/US sessions). **Key advantages:** - 0.5-4 days time savings - Multiple event types supported - Customizable layouts - Placeholder functionality **Resources:** [pharmaverse.github.io/examples/digit_files/autoslider.html](https://pharmaverse.github.io/examples/digit_files/autoslider.html) ------------------------------------------------------------------------ ## R Adoption & Strategy ### From Harmony to Hybrid: Charting a Course for R Adoption **Joe Zhu** Practical strategies for R adoption in pharmaceutical organizations. **Topics:** - Adoption frameworks - Hybrid approaches (SAS + R) - Change management - Success factors ------------------------------------------------------------------------ ### Emerging Trend of LLM Development in R **Mia Chen, Peng Zhang** Overview of Large Language Model implementation trends in R ecosystem. **Coverage:** - Current LLM packages in R - Integration patterns - Use cases in pharma - Future directions ------------------------------------------------------------------------ ## Specialized Applications ### An R Package for Pretest Probability Models for CAD **Jeremy Selva** Package consolidating pretest probability models and guidelines for Coronary Artery Disease. **Features:** - Multiple model implementations - Guideline integration - Clinical utility - Validation support ------------------------------------------------------------------------ ### Enhancing e-CRT Creation for PMDA with Vibe Coding **Naoki Yoshida** R Shiny app development for PMDA (Japan's regulatory agency) electronic Case Report Tabulation using innovative "Vibe Coding" approach. **Innovation:** - Rapid development methodology - Regulatory-ready outputs - User-friendly interface - Efficiency gains ------------------------------------------------------------------------ ## AI & Advanced Methods ### {meRlin}: Context-Aware AI Assistant for Clinical Programming **Steven Brooks, Pietro Mascheroni, Xiecheng Gu** AI assistant specifically designed for clinical programming workflows. **Capabilities:** - Context-aware code suggestions - Clinical programming patterns - Integration with development environment - Domain-specific knowledge ------------------------------------------------------------------------ ### Improving Precision Healthcare for Under-Represented Populations **Jimmy Breen** Application of R in advancing precision healthcare for genetically diverse and under-represented global populations. **Focus:** - Genetic diversity considerations - Population-specific analyses - Healthcare equity - Precision medicine approaches ------------------------------------------------------------------------ ### Exploring AI Tools in Clinical Trial Data Analysis **Terry Zhang** Survey and exploration of AI tools applicable to clinical trial data analysis. **Coverage:** - Available AI tools - Use case demonstrations - Integration strategies - Practical applications ------------------------------------------------------------------------ ### cgmguru: Automated Glycemic Event Detection **Sang Ho Park** R package for automated detection of glycemic events from continuous glucose monitoring data. **Features:** - Event detection algorithms - Automated analysis - Clinical relevance - Validation metrics ------------------------------------------------------------------------ ## Reporting & Documentation ### Interactive and Reproducible Reports with Quarto **Jaspreet Pabla** Creating interactive, reproducible clinical reports using Quarto. **Advantages:** - Multi-format output - Interactivity options - Reproducibility - Modern publishing ------------------------------------------------------------------------ ### Using ARD with {cards} for PMDA Oncology Inquiries **Shunsuke Goto** Application of Analysis Results Data using `{cards}` package for responding to PMDA oncology regulatory inquiries. **Benefits:** - Structured data approach - Rapid response capability - Consistency - Traceability ------------------------------------------------------------------------ ## Practical Tips & Tools ### Reach for R Low Hanging Fruit for Faster Results **Sunil Gupta** Identifying and implementing quick wins with R for immediate productivity gains. **Topics:** - Quick wins identification - Practical implementations - Efficiency improvements - Getting started tips ------------------------------------------------------------------------ ### MedxR Package: Bridging FDA and Health Canada Drug Data **Renzo Cáceres Rossi** R package providing access to regulatory drug data from FDA and Health Canada. **Features:** - Unified data access - API integration - Data standardization - Research facilitation ------------------------------------------------------------------------ ### risk.assessr: Extending Package Validation **Hugo Bottois** Extension of risk assessment tools for package validation processes. **Enhancements:** - Validation workflow support - Extended metrics - Integration capabilities - Reporting features ------------------------------------------------------------------------ ### Code Review for Compliance: Validated R Workflows **Alexandros Kouretsis** Best practices for code review in validated R workflows for pharmaceutical compliance. **Topics:** - Review strategies - Compliance requirements - Quality assurance - Documentation ------------------------------------------------------------------------ ### Web-Based R Application for Patient Enrollment Forecasting **Akifumi Okayama, Motoki Oe, Nobushige Matsuoka** Shiny application for forecasting patient enrollment in clinical trials. **Features:** - Forecasting models - Interactive interface - Scenario planning - Decision support ------------------------------------------------------------------------ ## 🔑 Regional Themes ### 1. Regulatory Focus Strong emphasis on PMDA (Japan) regulatory requirements with specialized tools and approaches. ### 2. Practical Implementation Focus on real-world applications and efficiency improvements in daily workflows. ### 3. AI Adoption Growing interest in AI/LLM tools tailored for clinical programming and analysis. ### 4. Open Source Movement Increasing adoption of open-source culture and collaborative development. ### 5. Cultural Considerations Presentations addressing unique challenges and opportunities in Asia/Pacific markets including: - Under-represented populations - Regional regulatory requirements - Local healthcare systems - Genetic diversity ------------------------------------------------------------------------ ## 📊 Topic Distribution :::::: {layout-ncol="3"} ::: stats-box **5** Automation & Tools ::: ::: stats-box **4** AI & Advanced Methods ::: ::: stats-box **4** Strategy & Culture ::: :::::: ------------------------------------------------------------------------ ## 🌏 Geographic Insights The Asia/Pacific presentations demonstrate: - **Strong R adoption** across major pharma companies in the region - **Innovation in automation** for regulatory compliance (especially PMDA) - **Focus on practical tools** addressing regional-specific needs - **Growing AI integration** in clinical workflows - **Emphasis on efficiency** and time-saving solutions ------------------------------------------------------------------------ *Asia/Pacific Presentations from R/Pharma 2025 Conference \| Last updated: November 2025*